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Tip of the Week

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The FDA has approved lorcaserin (10 mg orally twice daily) for weight loss (trade name: Belviq). It is a selective serotonin 2C receptor agonist that acts centrally to increase satiety, while avoiding the serotonin 2B receptor in heart valves (141). Specifically, lorcaserin stimulates pro-opiomelanocortin (POMC) neurons in the arcuate nucleus to release alpha-melanocortinstimulating hormone (a-MSH), which acts in the paraventricular nucleus to suppress appetite. In two randomized, placebo-controlled, phase 3 trials, weight loss over 1 year was 5%–6% (slightly less than that of Phen/Topiramate) (10). Routine cardiac echocardiography is not recommended since the RR of cardiac valvulopathy from lorcaserin versus placebo is 1.16 (95% CI, 0.81–1.67) (141). Although well tolerated, common adverse effects of lorcaserin are headache, nausea, dizziness, fatigue, dry mouth, and constipation.
 Medication are an adjunct to diet exercise

Paul Tapia M.D.

Diplomate of the American Board of Obesity Medicine

Reaching a milestone

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Just wanted to share a note from a patient who has reached a milestone in her quest to get healthier…….

Dr. Tapia,
Just wanted to share that for the first time in 17 years the scale finally registered a number less than 200. For all the other times that I gave up for various reasons in the struggle to lose weight, it finally makes sense with my behavior changes and your professional guidance. Thank you. Feel free to share with other patients if you like. I’m sure there are more like me that have battled to get below that 200 mark for years and might have come close but just never got there and gave up. My goal weight at first appeared forever far away and difficult to imagine what I might look like if I reached it, but now I say, “Game On!” I can see the goal and that drivea me even harder to get there. On top of it all, I’m still not allowed to work out, but learned that eating the right foods and the right portions all for the right reasons can still allow me to lose weight and feel great doing it.

Belviq

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To all my clients/patients:

There is a new weight loss medication called Belviq that was approved last year by the FDA for weight loss and maintenance. The medication is called Belviq. It is taken twice daily (before breakfast and before dinner).

Last night, I had a chance to read a Phase 3 clinical trial that was published in the New England Journal of Medicine. A Phase 3 Clinical trial is a study that confirms that a drug works and is safe when compared to placebo. It showed that patients taking Belviq lost a significant amount of weight when compared to people who were taking placebo (fake or sugar pills). The trial was blinded to both researcher and patient. In other words, neither the doctors nor the patient knew what medication they were taking until the clinical study was over.

I have a free two week trial and savings cards for anyone interested in trying Belviq. As you all know, my program is not about starving yourself, drinking shakes or fake drugs like HCG. It’s about changes in behaviors, eating habits and lifestyle change. In order to be successful (and to keep the weight off), you must change your habits. Behavioral change is my focus every time we meet. Please feel free to e-mail or call me with any questions.

Good start Shawn !

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Shawn: you lost 21 pounds in 2 weeks! Great job. You are eating 3 meals per day, making better choices and exercising.keep up the good work. See you next time.

Great job kelly !!

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Thus far, you have lost 32 pounds. You remain motivated and focused. Doing great !

Katrina !!

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Great hearing from you! You have dropped 30 pounds in 6 weeks! You have done great in spite of a very busy schedule of college and work. Keep it up!!

Good Job Mitch !!

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You have lost 53 pounds in 2 months! You are learning to eat healthy, while enjoyng an occasional slice of pizza. Keep up the good work. You have establsihed a very healthy routine of normal eating and exercise. Keep up the good work. PS: you are going to need a new wardrobe soon!

Casey !!

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Great seeing you today. Thus far, you have lost 55 pounds and look terrific!! Keep up the good work. You have definitely changed your lifestyle.

Great job Toni

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Thus far, you have lost 33 pounds. You continue to lose “double digits” every month. You have made changings in your behaviors and habits. Keep up the great work.

Great job Shane !

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You lost 15 pounds in 2 weeks by eating normal. Keep going. Looking forward to seeing what you do in one month!